![]() ![]() These updates have increased the speed of exams while preserving accuracy and reproducibility. Over time, the testing strategies implemented by the HFA instrument to evaluate VF loss have been refined through multiple iterations, seeking to alleviate the burden of frequent indicated testing 2, 3, 4 and to bridge the gap between recommended guidelines and clinical practice 5, 6, 7. Among the several methods of testing VF loss in clinical practice, the most widely used is standard automated perimetry with the Humphrey Field Analyzer (HFA Carl Zeiss Meditec). Visual field (VF) testing is an important modality for the diagnosis and monitoring of glaucoma, a leading cause of irreversible blindness globally 1. Eyes that transition from SITA Standard to SITA Faster in a real-world clinical setting have an increased likelihood of preserving patterns reflecting a normal VF and lower tendency to preserve patterns reflecting abnormal VF as compared to consecutive SITA Standard exams in the same eye. We found switching from SITA Standard to SITA Faster was associated with less preservation of VF loss (i.e., abnormal AT 2–4, 6–9, 11, 13, 14) relative to successive SITA Standard exams ( P value < 0.01) and was associated with relatively greater preservation of AT 1, the normal VF ( P value < 0.01). Archetypal analysis was used to derive composition weights of 16 clinically relevant VF patterns (i.e., archetypes (AT)) from patient VFs. In this study, we determined the effect of transitioning from SITA Standard to SITA Faster on VF loss patterns in glaucomatous eyes undergoing longitudinal VF testing in a real-world clinical setting. Furthermore, characterization of differences in localizable VF loss patterns between algorithms, rather than global summary measures, can be important for clinician interpretation when transitioning testing strategies. These differences may be relevant, especially in glaucoma, where VF changes over time influence clinical decisions around treatment. However, existing evidence suggests that there are some differences in global measures of VF loss in eyes transitioning from SITA Standard to the newer SITA Faster. ![]() Swedish Interactive Threshold Algorithm (SITA) Faster is the most recent and fastest testing algorithm for the evaluation of Humphrey visual fields (VF). ![]()
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